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DIRECT - Leaving daily usually at 17.00 and 19.30 (but times change - would still be in a similar time range though) from La Paz to Santa Cruz. Toilet, heating, proper reclinable seats and movies. Journey 18 hours approximately.

Bolivia's first hop-on/hop-off tourist bus service from La Paz to Copacabana to Puno to Arequipa with free Sun Island (Copacabana) tour. Flexible dates. Safe, reliable and fun! Daily departures from La Paz, 6 departures per week from Copacabana to Puno and 4 from Puno to Arequipa. Floating Islands tour from Puno available for an extra price.

Peru's first hop-on/hop-off tourist bus service from Lima to Arequipa including stops in Paracas, Huacachina and Nazca (Lima to Canyon). Flexible dates. Safe, reliable and fun!  Daily departures from Lima and Paracas, 4 departures per week from Huacachina.

The La Paz to Santa Cruz de la Sierra flight (Viru Viru airport) is a stunning journey over the Cordillera Real mountains and down to this beautiful city - largest city in Bolivia. The flight takes around 60 minutes and it is the fastest and most comfortable way to Santa Cruz. Book early in busy season! This flight is operated by Amaszonas Airlines.

Catch a direct flight from Sucre to Santa Cruz, the fastest and most comfortable way avoiding a 12 hours bus ride. This flight is operated by BoA Airlines (Boliviana de Aviación). Flight schedules change from day to day but as a general guide there are four flights per day, two in the morning and two in the afternoon.